March 2021 newsletter Fall2020 Cohort at Berkeley Skydeck Accelerator Delivery Nucleic Acids for Research and Beyond RJH Biosciences aims to provide the best transfection reagents for your experimental endeavors. We work closely with our customers and collaborators to ensure that their precious nucleic acid cargo is effectively transported into target cells, every time. Our mission is to… Continue reading May 2021 Newsletter
March 2021 newsletter “One to Watch” in the Nature Spinoff Prize 2020 Delivery of Nucleic Acids with RJH Biosciences Reagents RJH Biosciences facilitates delivery of nucleic acids to biological systems, including siRNA, mRNA, pDNA, miR and ASO. Our polymeric reagents provide stable and effective delivery of polynucleotides in various cell types and animal models. RJH reagents allow your studies in cell culture and animal models to be… Continue reading March 2021 newsletter
Reagents for Antisense Oligonucleotide (ASO) Delivery Application Note: Use of RJH Transfection Reagents in Antisense Oligonucleotide (ASO) Delivery BACKGROUND The convergences of sophisticated delivery systems, oligonucleotide chemistry and genetic bioinformatics has significantly enhanced the exploration of antisense oligonucleotides (ASO) for therapeutic purposes, which has been reflected in many clinical studies (Nat. Rev. Drug Discov. 11,… Continue reading Reagents for Antisense Oligonucleotide (ASO) Delivery
Comparing Lipofection to RJH Reagents Application Note: Comparison of Transfection Reagents for pDNA and mRNA Delivery BACKGROUND Peripheral blood derived mononuclear cells (PBMCs) are important mediators involved in immune surveillance and are actively explored as the foundation of a wide range of therapies [1]. It is convenient to isolate the cells from patients and re-administer… Continue reading Comparing Lipofection to RJH Reagents
mRNA Modification of PBMCs Application Note: Use of RJH Transfection Reagents for mRNA Delivery to PBMCs BACKGROUND Peripheral blood derived mononuclear cells (PBMCs) are important mediators involved in immune surveillance and are actively explored as the foundation of a wide range of therapies [1]. It is convenient to isolate the cells from patients and re-administer… Continue reading mRNA Modification of PBMCs
mRNA-Fect Transfection Reagent to Deliver mRNA in Breast Cancer Cells Application Note: mRNA-Fect Transfection Reagent to Deliver mRNA in Breast Cancer Cells BACKGROUND Messenger RNA (mRNA) therapy has been developed as an alternative to DNA-based therapies as it avoids several limiting issues associated with the DNA delivery. It can efficiently modify hard-to-transfect non-dividing cells since… Continue reading mRNA-Fect Transfection Reagent to Deliver mRNA in Breast Cancer Cells
Transfecting Triple-Negative Breast Cancer MDA-MB-231 Cells with Plasmid DNA and siRNA by using ALL-Fect and Prime-Fect Application Note: Transfecting Triple-Negative Breast Cancer MDA-MB-231 Cells with Plasmid DNA and siRNA by using ALL-Fect and Prime-Fect Phase Contrast (top) and Fluorescence Microscopy (bottom) pictures of breast cancer cells transfected with a leading polymeric reagent and ALL-Fect. A leading… Continue reading Transfecting Triple-Negative Breast Cancer MDA-MB-231 Cells with Plasmid DNA and siRNA by using ALL-Fect and Prime-Fect
Use of RJH Transfection Reagents in Co-Delivery of Plasmid DNA and short interfering RNA Application Note: Use of RJH Transfection Reagents in Co-Delivery of Plasmid DNA and short interfering RNA BACKGROUND The convergence genetic bioinformatics and nucleic acid (DNA and RNA) chemistry with sophisticated delivery systems has significantly enhanced therapeutic application of nucleic acids. The… Continue reading Use of RJH Transfection Reagents in Co-Delivery of Plasmid DNA and short interfering RNA
RJH Transfection Reagents in siRNA Library Screens Application Note: RJH Transfection Reagents in siRNA Library Screens BACKGROUND The structured oligonucleotide libraries allow one to screen large number of compounds for specific purposes. In biomarker discovery, library screens facilitate identification of critical mediators that are responsible for pathological conditions. In therapeutic discovery, library screens allow one… Continue reading RJH Transfection Reagents in siRNA Library Screens
microRNA Delivery to Leukemic Cells Use of RJH Transfection Reagents to Deliver microRNAs into Leukemic Cells BACKGROUND The convergence of genetic bioinformatics and nucleic acid chemistry along with sophisticated transfection systems have significantly expanded scientific and therapeutic applications of nucleic acids. The newly emerging non-coding RNAs, so called microRNAs (miRNAs), are gaining tremendous attention as… Continue reading microRNA Delivery to Leukemic Cells
RJH manufactures a variety of transfection agents for your R&D needs. Download our catalogue for a list of our products.
