At RJH Biosciences, we develop non-viral, polymer-based nucleic acid delivery systems designed for efficient transfection of primary and hard-to-transfect cells. Our platform enables robust delivery of a range of nucleic acids with consistent performance across diverse primary cells. The RJH reagents achieve strong and reproducible gene expression in primary and murine cell models, outperforming commercial… Continue reading May 2026 | Efficient Nucleic Acid Delivery in Primary Cells
RJH Biosciences provides polymer-based transfection solutions supporting RNA and DNA delivery across cell lines, primary cells, and in vivo models. This edition highlights recent client work, including high-throughput polymer screening for siRNA delivery and functional siRNA library screening in human breast cancer and fibroblast cells. Screening for Optimal Delivery Formulation Three polymeric delivery systems were… Continue reading March 2026 | Delivery Insights: RJH Biosciences Contract Services
Polymer-Based Solutions for Effective In Vivo mRNA Delivery At RJH Biosciences, we develop non-viral, polymer-based delivery platforms engineered for efficient and reproducible mRNA delivery across in vivo biological systems. Our technologies support functional mRNA expression in animal models and are designed to enable systemic delivery, consistent performance, and broad applicability across research and therapeutic development… Continue reading February 2026 | Advancing mRNA Delivery In Vivo: New Animal Study Results
At RJH Biosciences, we develop non-viral, polymer-based transfection technologies optimized for delivery of nucleic acids across a wide range of modalities. Our platforms enable efficient and reproducible delivery in established cell lines, primary cells, and in vivo models, supporting fundamental research as well as therapeutic development. Overview of RJH Biosciences transfection reagents across nucleic acid… Continue reading January 2026 | Polymer-Based Solutions for Strong RNA and DNA Delivery Across Biological Systems
Learn how our polymer-based transfection reagents enable CRISPR activity and open new possibilities for gene editing. Engineered for high-efficiency gene editing. GFP Knockout CRISP-Fect: Functional Knockout Validated by qPCR About CRISP-Fect and Genome Editing Delivery CRISP-Fect is a polymer-based transfection platform developed by RJH Biosciences to support efficient delivery of CRISPR components, including Cas9 mRNA, sgRNA, and… Continue reading December 2025 | CRISP-Fect: A Polymer-Based Platform for Efficient CRISPR Genome Editing
Strong mRNA expression and siRNA silencing across multiple organs demonstrate the superior performance and reliability of RJH’s delivery technology. Robust Multi-Organ mRNA Expression mRNA-Fect Ultra enabled robust in vivo luciferase mRNA expression following intraperitoneal administration. Whole-animal images (left) and organ-level luminescence quantitation (right) show high, consistent expression across key tissues. Efficient In Vivo siRNA Delivery… Continue reading October 2025 | Proven In Vivo Performance for mRNA and siRNA Delivery
Efficient delivery leads to protein expression and functional outcomes from primary human blood cells. Effective mRNA Delivery to PBMCs PBMCs were transfected with GFP mRNA using mRNA-Fect ULTRA and compared against a leading commercial reagent. mRNA-Fect ULTRA achieved markedly higher GFP expression demonstrating superior efficiency in these hard-to-transfect immune cells. PBMCs Secrete Functional TRAIL PBMCs… Continue reading September 2025 | mRNA Delivery to Drive PBMC Functionality
Killing Lung Cancer A549 Cells with RJH Reagents and Cytotoxic siRNAs Testimonial: mRNA Killing Lung Cancer A549 Cells with RJH Reagents and Cytotoxic siRNAs Background Lung cancer is a deadly disease. Cancers originating in lungs or metastasized to lungs from other sites are particularly difficult to treat due to several mechanisms that facilitate cancer cells… Continue reading Killing Lung Cancer A549 Cells with RJH Reagents and Cytotoxic siRNAs
mRNA Transfection of Endothelial Cells with RJH Reagents Testimonial: mRNA Transfection of Endothelial Cells with RJH Reagents Background Delivering messenger RNA (mRNA) is a new approach for rapid expression and secretion of proteins in human cells. It is providing a more effective alternative to plasmid DNA based expression systems since it may not be necessary… Continue reading mRNA Transfection of Endothelial Cells with RJH Reagents
Transfecting Human Astrocytes with RJH Reagents: GFP Expression and siRNA Uptake Testimonial: Transfecting Human Astrocytes with RJH Reagents: GFP Expression and siRNA Uptake Background Astrocytes is an important cell type that participates in hemostasis of brain tissue. They perform several functions, including biochemical support of endothelial cells that form the blood brain barrier, nutrient support… Continue reading Transfecting Human Astrocytes with RJH Reagents:
GFP Expression and siRNA Uptake
RJH manufactures a variety of transfection agents for your R&D needs. Download our catalogue for a list of our products.
