At RJH Biosciences, we develop non-viral, polymer-based transfection technologies optimized for delivery of nucleic acids across a wide range of modalities. Our platforms enable efficient and reproducible delivery in established cell lines, primary cells, and in vivo models, supporting fundamental research as well as therapeutic development.
Overview of RJH Biosciences transfection reagents across nucleic acid modalities and biological systems. Our platforms support delivery of siRNA, mRNA, DNA, and CRISPR cargoes in cell lines, primary cells, and in vivo models.
In vivo biodistribution of mRNA delivered with RJH reagents mRNA-Fect and mRNA-Fect kit. Systemic administration demonstrates effective tissue-level delivery, highlighting the versatility of RJH reagents beyond traditional LNP-based approaches.
In Vivo siRNA Biodistribution
- Efficient siRNA delivery and tissue distribution following systemic administration
- Highlights the flexibility of RJH platform for in vivo RNA applications
Plasmid DNA Transfection in Neuro2A Cells
- Neuro2A cells were transfected with GFP-expressing pDNA using RJH All-Fect or Lipofectamine™ 2000
- Flow cytometry analysis showed high transfection efficiencies achieved with All-Fect
Advancing RNA & DNA Delivery with Polymer-Based Transfection
Polymer-based transfection systems are transforming non-viral gene delivery by enabling efficient transport of mRNA, siRNA, and plasmid DNA across diverse cell types. With tunable chemistries that enhance stability, cellular uptake, and endosomal escape, these platforms offer a flexible and scalable alternative to traditional methods.
As demand grows for high-throughput screening and reproducible gene modulation, polymer-based solutions continue to support breakthroughs in functional genomics, cancer research, and RNA-based therapeutics.
At RJH Biosciences, we specialize in customizable polymer-based transfection solutions designed to optimize delivery across challenging cell models and experimental systems—helping accelerate your research from screening to discovery.
